There is a negative correlation between mean dose to PCM and mean MDADI score.Ĭonclusion: All cases of head and neck cancer where swallowing structures are irradiated and late dysphagia is suspected, Do-IMRT technique can be adopted for improvement of dysphagia and quality of life. Patients in Do-IMRT arm have less Ryles tube dependence compared to the S-IMRT arm. Results: There is a significant improvement in the MDADI score in the Do-IMRT arm compared to S-IMRT arm at six months after completion of radiation. Assessment of dysphagia using MD Anderson Dysphagia Inventory (MDADI) score and associated QOL was done pre-RT, three months and six months post-RT. All patients received standard radiation dose alongside weekly cisplatin. In Do-IMRT arm, a mean dose constraint of 50Gy was given to Pharyngeal constrictors (PCM). CT simulations were taken, contouring of target volumes and OARs were done. Materials and methods: This single institution study with patients satisfying all inclusion and exclusion criteria were randomised in 1:1 ratio into Do-IMRT and S-IMRT arms. Primary objective of the study was to determine whether limiting the radiation dose to DARS using Do-IMRT improves swallowing compared to S-IMRT in head and neck cancer patients and secondary objectives were to find out a correlation between dysphagia associated Quality of Life (QOL) and radiation dose to DARS. Aims and Objectives: The aim of this study was to determine how the dose received by Dysphagia/Aspiration at risk structures (DARS) affects swallowing in patients with head and neck cancer treated using IMRT.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |